| Adrien de Wignacourt | |
| Office: | Grand Master of the Order of Saint John |
| Term Start: | 24 July 1690 |
| Term End: | 4 February 1697 |
| Predecessor: | Gregorio Carafa |
| Successor: | Ramon Perellos y Roccaful |
| Birth Date: | 1618 |
| Birth Place: | France |
| Death Date: | 4 February 1697 |
| Death Place: | Malta |
| Restingplace: | St. John's Co-Cathedral |
| Nationality: | French |
| Allegiance: | Order of Saint John |
Fra' Adrien de Wignacourt (1618 – 4 February 1697) was the 63rd Prince and Grand Master of the Order of Malta from 1690 to 1697.[1]
He was the nephew of Fra Alof de Wignacourt. He was elected Grand Master after the death of Fra Gregorio Carafa in 1690.
He died in 1697[2] and was succeeded by Fra Ramon Perellos.