| Gwune | |
| Nativename: | Agwagwune |
| States: | Nigeria |
| Region: | Cross River State |
| Speakers: | 20,000 |
| Date: | 1973 |
| Ref: | e25 |
| Familycolor: | Niger-Congo |
| Fam2: | Atlantic–Congo |
| Fam3: | Benue–Congo |
| Fam4: | Cross River |
| Fam5: | Upper Cross |
| Fam6: | Central |
| Fam7: | North–South |
| Fam8: | Ubaghara–Kohumono |
| Iso3: | yay |
| Glotto: | agwa1247 |
| Glottorefname: | Agwagwune |
The Gwune language, also known as Agwagwune, is an Upper Cross River language of Nigeria spoken by the Akunakuna people. It is a dialect cluster named after its prestige variety; others are Abayongo, Abini, Dim (Adim), Orum, Erei, Etono.