Adenosine receptor agonist explained

An adenosine receptor agonist is a drug which acts as an agonist of one or more of the adenosine receptors. Examples include the neurotransmitter adenosine, its phosphates, adenosine monophosphate (AMP), adenosine diphosphate (ADP), and adenosine triphosphate (ATP), and the pharmaceutical drug regadenoson.

List of adenosine receptor agonists

• ATL146e (A2A selective)^[1]
• PD81,723 (A1 allosteric enhancer)
• CF102 (Adenosine A3 receptor)^[2]
• Rosmarinic acid (A1 agonist)^[3]

See also

• Adenosine receptor antagonist
• Adenosine reuptake inhibitor

Notes and References

1. Glover . David K. . Riou . Laurent M. . Ruiz . Mirta . Sullivan . Gail W. . Linden . Joel . Rieger . Jayson M. . Macdonald . Timothy L. . Watson . Denny D. . Beller . George A. . Reduction of infarct size and postischemic inflammation from ATL-146e, a highly selective adenosine A 2A receptor agonist, in reperfused canine myocardium . American Journal of Physiology. Heart and Circulatory Physiology . April 2005 . 288 . 4 . H1851–H1858 . 10.1152/ajpheart.00362.2004. 15591104 .
2. Cohen . S. . Stemmer . S.M. . Zozulya . G. . Ochaion . A. . Patoka . R. . Barer . F. . Bar-Yehuda . S. . Rath-Wolfson . L. . Jacobson . K.A. . Fishman . P. . CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver . Journal of Cellular Physiology . September 2011 . 226 . 9 . 2438–2447 . 10.1002/jcp.22593. 21660967 . 3474360 .
3. Kim . Tae-Ho . Bormate . Katrina Joy . Custodio . Raly James Perez . Cheong . Jae Hoon . Lee . Bo Kyung . Kim . Hee Jin . Jung . Yi-Sook . February 2022 . Involvement of the adenosine A1 receptor in the hypnotic effect of rosmarinic acid . Biomedicine & Pharmacotherapy . 146 . 112483 . 10.1016/j.biopha.2021.112483 . 1950-6007 . 34891112. free .