Acylaminoacyl-peptidase explained

Acylaminoacyl-peptidase
Ec Number:3.4.19.1
Cas Number:73562-30-8

Acylaminoacyl-peptidase (acylamino-acid-releasing enzyme, N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, alpha-N-acylpeptide hydrolase) is an enzyme.[1] [2] [3] This enzyme catalyses the following chemical reaction

Cleavage of an N-acetyl or N-formyl amino acid from the N-terminus of a polypeptide

This enzyme is active at neutral pH.

Notes and References

  1. Tsunasawa S, Narita K, Ogata K . Purification and properties of acylamino acid-releasing enzyme from rat liver . Journal of Biochemistry . 77 . 1? . 89–102 . January 1975 . 1137989 .
  2. Unger T, Nagelschmidt M, Struck H . N-Acetylaminoacyl-p-nitranilidase from human placenta. Purification and some properties . European Journal of Biochemistry . 97 . 1 . 205–11 . June 1979 . 477668 . 10.1111/j.1432-1033.1979.tb13104.x . free .
  3. Kobayashi K, Smith JA . Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction . The Journal of Biological Chemistry . 262 . 24 . 11435–45 . August 1987 . 3305492 .

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