Acute leukemia explained

Synonym:	-->
Cause:	-->
Risk:	-->
Management:	-->
Incidence:	or
Prevalence:	-->

Acute leukemia or acute leukaemia is a family of serious medical conditions relating to an original diagnosis of leukemia. In most cases, these can be classified according to the lineage, myeloid or lymphoid, of the malignant cells that grow uncontrolled, but some are mixed and for those such an assignment is not possible.^[1]

Forms of acute leukemia include:

• Acute myeloid leukemia (AML),^[2] a rare form of which is acute erythroid leukemia.^[3]
• Acute lymphoblastic leukemia (ALL)^[4] including T-cell acute lymphoblastic leukemia.^[5] Types of T-cell acute lymphoblastic leukemia include adult T-cell leukemia/lymphoma^{[6] [7] [8]} and (precursor) T-lymphoblastic leukemia/lymphoma.
• Blast crisis of chronic myelogenous leukemia.

Medical statistics

Based on data from United States Cancer Statistics (USCS) Public Use Database for 2001-2017, the 2021 estimate for new cases of AML and ALL are following:^[9]

• Total estimated cases for AML: 20,240
• Total estimated cases for ALL: 5,690

Based on these estimates, AML is about 78% of the total cases.

Notes and References

1. 25605373. 2015. Wolach. O. How I treat mixed-phenotype acute leukemia. Blood. 125. 16. 2477–85. Stone. R. M.. 10.1182/blood-2014-10-551465. free.
2. Web site: Acute Myeloid Leukemia . 11 August 2021 . The Lecturio Medical Concept Library.
3. Zuo Z, Polski JM, Kasyan A, Medeiros LJ . Acute erythroid leukemia . Arch. Pathol. Lab. Med. . 134 . 9 . 1261–70 . 2010 . 20807044 . 10.5858/2009-0350-RA.1 . free .
4. Web site: Acute Lymphoblastic Leukemia . 11 August 2021 . The Lecturio Medical Concept Library.
5. Litzow. Mark R.. Ferrando. Adolfo A.. 2015-08-13. How I treat T-cell acute lymphoblastic leukemia in adults. Blood. en. 126. 7. 833–841. 10.1182/blood-2014-10-551895. 25966987. 0006-4971. free.
6. 572–3 . 10.1056/NEJM197403072901018 . Letter: Two cases of T-cell chronic lymphocytic leukemia in Japan . 1974 . New England Journal of Medicine . 290 . 10 . 4544052 . Yodoi . J . Takatsuki . K . Masuda . T.
7. 301762 . 1977 . Uchiyama . T . Yodoi . J . Sagawa . K . Takatsuki . K . Uchino . H . Adult T-cell leukemia: Clinical and hematologic features of 16 cases . 50 . 3 . 481–92 . Blood. 10.1182/blood.V50.3.481.481 . free .
8. 423–8 . 10.1007/s12185-011-0957-x . The discovery of ATL: an odyssey in restrospect . 2011 . International Journal of Hematology . 94 . 5 . 22068231 . Yodoi . J . Maeda . M. 9299403 .
9. Web site: Facts 2020-2021 .