| Official Name: | Acme, Indiana |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | Indiana#USA |
| Pushpin Label: | Acme |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Indiana |
| Subdivision Type2: | County |
| Subdivision Name2: | Jackson |
| Subdivision Type3: | Township |
| Subdivision Name3: | Hamilton |
| Population As Of: | 2000 |
| Population Total: | 30 |
| Coordinates: | 38.9781°N -86.0589°W |
| Elevation Ft: | 610 |
| Postal Code Type: | ZIP code |
| Postal Code: | 47274 |
| Blank Name: | FIPS code |
| Blank Info: | 18-00244[1] |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 429998 |
Acme is an unincorporated community in Hamilton Township, Jackson County, Indiana.
A post office was established in Acme in 1884, and remained in operation until it was discontinued in 1891.[2] Acme is likely derived from a Greek word meaning "best".[3]