Achilleol B synthase explained

Achilleol B synthase
Ec Number:	5.4.99.48

Achilleol B synthase is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, achilleol-B-forming).^[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene

\rightleftharpoons achilleol B

Achilleol B is probably formed by cleavage of the 8-14 and 9-10 bonds of (3S)-2,3-epoxy-2,3-dihydrosqualene.

Notes and References

1. Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T . Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases . Organic Letters . 13 . 10 . 2678–81 . May 2011 . 21526825 . 10.1021/ol200777d .