Acanthocystis turfacea chlorella virus 1 explained

Acanthocystis turfacea chlorella virus 1 (ATCV-1), also called Chlorovirus ATCV-1 or Chlorella virus ATCV-1 is a species of giant double-stranded DNA virus in the genus Chlorovirus.

The host of ATCV-1 is Chlorella heliozoae; it was demonstrated that "ATCV-1 neither attaches to nor infects" Chlorella variabilis.[1] [2]

Human infection

DNA from ATCV-1 has been isolated from the mucous membranes of the noses of humans. In both humans and mice, the presence of ATCV-1 on the oropharyngeal mucosa was associated with lower scores in tests of cognitive and motor skills.[3] [4] Injection of purified algal virus ATCV-1 intracranially results in long-lasting cognitive and behavioural effects in mice via induction of inflammatory factors.[5]

External links

Notes and References

  1. Irina Agarkova . Brigitte Hertel . Xinzheng Zhang . Les Lane . Alexander Tchourbanov . David D. Dunigan . Gerhard Thiel . Michael G. Rossmann . James L. Van Etten . 2014. Dynamic attachment of Chlorovirus PBCV-1 to Chlorella variabilis. Virology. 466-467. 95–102 . 4254200. 25240455. 10.1016/j.virol.2014.07.002.
  2. Web site: SAG 211-6 Chlorella variabilis. EPSAG The Culture Collection of Algae at the University of Göttingen, Germany. 2017-09-23. 2017-09-23. https://web.archive.org/web/20170923144752/http://www.straininfo.net/strains/822477/browser. dead.
  3. 10.1073/pnas.1418895111. Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice. Proc Natl Acad Sci U S A . 2014. Yolken . R. H.. Jones-Brando . L.. Dunigan . D. D.. Kannan . G.. Dickerson . F.. Severance . E.. Sabunciyan . S.. Talbot . C. C.. Prandovszky . E.. Gurnon . J. R.. Agarkova . I. V.. Leister . F.. Gressitt . K. L.. Chen . O.. Deuber . B.. Ma . F.. Pletnikov . M. V.. Van Etten . J. L. . 25349393 . 4234575 . 111 . 45. 16106–11. 2014PNAS..11116106Y. free.
  4. Yolken. et al. Reply to Kjartansdóttir et al.: Chlorovirus ATCV-1 findings not explained by contamination. Proceedings of the National Academy of Sciences. 112. 9. E927. 4352770. 25654982. 10.1073/pnas.1424665112. 2015. 2015PNAS..112E.927Y. free.
  5. Marilyn S. Petro . Irina V. Agarkova . Thomas M.Petro . May 2016 . Effect of Chlorovirus ATCV-1 infection on behavior of C57Bl/6 mice . Journal of Neuroimmunology . 297 . 46–55 . 10.1016/j.jneuroim.2016.05.009 . 27397075. 38573451 .

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