| Abuna River | |
| Map: | Rio Negro map.jpg |
| Map Size: | 300 |
| Pushpin Map: | Bolivia |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Mouth in Bolivia |
| Subdivision Type1: | Country |
| Subdivision Name1: | Bolivia, Brazil |
| Subdivision Type3: | Region |
| Subdivision Name3: | Pando Department |
| Length: | 500km (300miles)[1] |
| Mouth: | Madeira River |
| Mouth Coordinates: | -9.6717°N -65.4464°W |
The Abuna River (Spanish; Castilian: Río Abuná, Portuguese: Rio Abunã) is a river in South America. As a part of the Amazon Basin, it forms part of the border between northern Bolivia and north-western Brazil.
The river has a total length of . It originates in several streams east of the Cordillera Oriental of the Peruvian Andes. The river is navigable for circa in its lower northeastern part. At Manoa it joins the Río Madeira, a tributary of the Amazon. Opposite the river mouth is the town of Abunã on the Brazilian side of the confluence.