ARIH1 explained
Protein ariadne-1 homolog is a protein that in humans is encoded by the ARIH1 gene.[1] [2]
Interactions
ARIH1 has been shown to interact with:
Further reading
- Aguilera M, Oliveros M, Martínez-Padrón M, Barbas JA, Ferrús A . Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins . Genetics . 155 . 3 . 1231–44 . 2000 . 10.1093/genetics/155.3.1231 . 10880484 . 1461160 .
- Zhang Y, Redina O, Altshuller YM, Yamazaki M, Ramos J, Chneiweiss H, Kanaho Y, Frohman MA . Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them . J. Biol. Chem. . 275 . 45 . 35224–32 . 2001 . 10926929 . 10.1074/jbc.M003329200. free.
- Tan NG, Ardley HC, Rose SA, Leek JP, Markham AF, Robinson PA . Characterisation of the human and mouse orthologues of the Drosophila ariadne gene . Cytogenet. Cell Genet. . 90 . 3–4 . 242–5 . 2001 . 11124525 . 10.1159/000056780. 12113119 .
- Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G . Characterization of 16 novel human genes showing high similarity to yeast sequences . Yeast . 18 . 1 . 69–80 . 2001 . 11124703 . 10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. 21397515 . free .
- Ardley HC, Tan NG, Rose SA, Markham AF, Robinson PA . Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7 . J. Biol. Chem. . 276 . 22 . 19640–7 . 2001 . 11278816 . 10.1074/jbc.M011028200. free .
- Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR . Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling . EMBO J. . 21 . 18 . 4796–808 . 2002 . 12234920 . 126289 . 10.1093/emboj/cdf493.
- Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA . Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP . FEBS Lett. . 554 . 3 . 501–4 . 2003 . 14623119 . 10.1016/S0014-5793(03)01235-3. 25441190 .
- Capili AD, Edghill EL, Wu K, Borden KL . Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING . J. Mol. Biol. . 340 . 5 . 1117–29 . 2004 . 15236971 . 10.1016/j.jmb.2004.05.035 .
- Parelkar SS, Cadena JG, Kim C, Wang Z, Sugal R, Bentley B, Moral L, Ardley HC, Schwartz LM . The parkin-like human homolog of Drosophila ariadne-1 (HHARI) can induce aggresome formation in mammalian cells and is immunologically detectable in Lewy bodies. . J. Mol. Neurosci. . 46 . 1 . 109–21 . 2012 . 21590270 . 10.1007/s12031-011-9535-1 . 17276111 .
Notes and References
- Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA . The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1 . J Biol Chem . 274 . 43 . 30963–8 . November 1999 . 10521492 . 10.1074/jbc.274.43.30963 . free .
- Web site: Entrez Gene: ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila).
- Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA . Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP . FEBS Lett. . 554 . 3 . 501–4 . November 2003 . 14623119 . 10.1016/s0014-5793(03)01235-3. 25441190 .
- Ardley HC, Tan NG, Rose SA, Markham AF, Robinson PA . Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7 . J. Biol. Chem. . 276 . 22 . 19640–7 . June 2001 . 11278816 . 10.1074/jbc.M011028200 . free .
