APOL6 explained

Apolipoprotein L6 is a protein that in humans is encoded by the APOL6 gene.^{[1] [2]}

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.^[3]

Further reading

• Bonaldo MF, Lennon G, Soares MB . Normalization and subtraction: two approaches to facilitate gene discovery. . Genome Res. . 6 . 9 . 791–806 . 1997 . 8889548 . 10.1101/gr.6.9.791 . free .
• Dominguez O, Ashhab Y, Sabater L . Cloning of ARE-containing genes by AU-motif-directed display. . Genomics . 54 . 2 . 278–86 . 1999 . 9828130 . 10.1006/geno.1998.5548 . etal.
• Dunham I, Shimizu N, Roe BA . The DNA sequence of human chromosome 22. . Nature . 402 . 6761 . 489–95 . 1999 . 10591208 . 10.1038/990031 . 1999Natur.402..489D . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Clark HF, Gurney AL, Abaya E . The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Collins JE, Wright CL, Edwards CA . A genome annotation-driven approach to cloning the human ORFeome . Genome Biol. . 5 . 10 . R84 . 2005 . 15461802 . 10.1186/gb-2004-5-10-r84 . 545604 . etal . free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.

Notes and References

1. Page NM, Butlin DJ, Lomthaisong K, Lowry PJ . The human apolipoprotein L gene cluster: identification, classification, and sites of distribution . Genomics . 74 . 1 . 71–8 . May 2001 . 11374903 . 10.1006/geno.2001.6534 .
2. Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA . Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells . Mol Cancer Res . 3 . 1 . 21–31 . Jan 2005 . 10.1158/1541-7786.21.3.1 . 15671246 . 2545675 . free .
3. Web site: Entrez Gene: APOL6 apolipoprotein L, 6.