APOBEC2 explained

Probable C->U-editing enzyme APOBEC-2 is a protein that in humans is encoded by the APOBEC2 gene.^{[1] [2]}

Further reading

• Wedekind JE, Dance GS, Sowden MP, Smith HC . Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. . Trends Genet. . 19 . 4 . 207–16 . 2003 . 12683974 . 10.1016/S0168-9525(03)00054-4 .
• Lau PP, Zhu HJ, Baldini A . Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene . Proc. Natl. Acad. Sci. U.S.A. . 91 . 18 . 8522–6 . 1994 . 8078915 . 10.1073/pnas.91.18.8522 . 44638 . 1994PNAS...91.8522L . etal. free .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Oka K, Kobayashi K, Sullivan M . Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice . J. Biol. Chem. . 272 . 3 . 1456–60 . 1997 . 8999814 . 10.1074/jbc.272.3.1456 . etal. free.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 . etal.
• Anant S, Mukhopadhyay D, Sankaranand V . ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing . Am. J. Physiol., Cell Physiol. . 281 . 6 . C1904–16 . 2001 . 11698249 . 10.1152/ajpcell.2001.281.6.C1904. 7343760 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Mungall AJ, Palmer SA, Sims SK . The DNA sequence and analysis of human chromosome 6 . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Prochnow C, Bransteitter R, Klein MG . The APOBEC-2 crystal structure and functional implications for the deaminase AID . Nature . 445 . 7126 . 447–51 . 2007 . 17187054 . 10.1038/nature05492 . 2007Natur.445..447P . 4394772 . etal.

Notes and References

1. Liao W, Hong SH, Chan BH, Rudolph FB, Clark SC, Chan L . APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family . Biochem Biophys Res Commun . 260 . 2 . 398–404 . Aug 1999 . 10403781 . 10.1006/bbrc.1999.0925 .
2. Web site: Entrez Gene: APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2.