AP20187 explained

AP20187 is a ligand that can induce homodimerization of fusion proteins containing the F36V mutant of an FKBP domain(FKBPF36V),^[1] available commercially as the DmrB domain.^{[2] [3]}

Notes and References

1. Kawahara. Masahiro. Mabe. Satoru. Nagamune. Teruyuki. Detecting protein–protein interactions based on kinase-mediated growth induction of mammalian cells. Scientific Reports. 2014 . 10.1038/srep06127. 4. 6127. 25135216 . 4137342.
2. Web site: Dimerizer Ligands - B/B Homodimerizer (AP20187), A/C Heterodimerizer (AP21967), D/D Solubilizer (AP21998), B/B Washout Ligand . Clontech.com . February 5, 2016.
3. AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice. 17328681 . 10.1089/hum.2006.116 . 18 . Hum Gene Ther . 106–17 . Cotugno . G . Formisano . P . Giacco . F . Colella . P . Beguinot . F . Auricchio . A. 2007 . 2 .