ANAPC11 explained

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.^{[1] [2]}

Interactions

ANAPC11 has been shown to interact with ANAPC2^{[3] [4]} and CDC27.^[5]

Further reading

• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Chang TS, Jeong W, Lee DY . The RING-H2-finger protein APC11 as a target of hydrogen peroxide. . Free Radic. Biol. Med. . 37 . 4 . 521–30 . 2005 . 15256223 . 10.1016/j.freeradbiomed.2004.05.006 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Vodermaier HC, Gieffers C, Maurer-Stroh S . TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. . Curr. Biol. . 13 . 17 . 1459–68 . 2004 . 12956947 . 10.1016/S0960-9822(03)00581-5 . 5942532 . etal. free . 2003CBio...13.1459V .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . etal. 2002PNAS...9916899M . free .
• Tang Z, Li B, Bharadwaj R . APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex. . Mol. Biol. Cell . 12 . 12 . 3839–51 . 2002 . 11739784 . 10.1091/mbc.12.12.3839. 60759 . etal.
• Chan AH, Lee SM, Chim SS . Molecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p. . J. Cell. Biochem. . 83 . 2 . 249–58 . 2001 . 11573242 . 10.1002/jcb.1217 . 45073069 . etal. free .
• Zhang QH, Ye M, Wu XY . Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. . Genome Res. . 10 . 10 . 1546–60 . 2001 . 11042152 . 10.1101/gr.140200 . 310934 . etal.

Notes and References

1. Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM . The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex . Proc Natl Acad Sci U S A . 97 . 16 . 8973–8 . Sep 2000 . 10922056 . 16806 . 10.1073/pnas.97.16.8973 . 2000PNAS...97.8973G . free .
2. Web site: Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast).
3. Tang . Z . Li B . Bharadwaj R . Zhu H . Ozkan E . Hakala K . Deisenhofer J . Yu H . Dec 2001 . APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex . Mol. Biol. Cell . 12 . 12 . 3839–51 . United States. 1059-1524. 11739784 . 60759 . 10.1091/mbc.12.12.3839.
4. 10.1016/S1097-2765(00)80482-7 . Ohta . T . Michel J J . Schottelius A J . Xiong Y . Apr 1999 . ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity . Mol. Cell . 3 . 4 . 535–41 . UNITED STATES. 1097-2765. 10230407 . 19371828 . free .
5. 10.1016/S0960-9822(03)00581-5 . Vodermaier . Hartmut C . Gieffers . Christian . Maurer-Stroh . Sebastian . Eisenhaber . Frank . Peters . Jan-Michael . Sep 2003 . TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 . Curr. Biol. . 13 . 17 . 1459–68 . England. 0960-9822. 12956947 . 5942532 . free . 2003CBio...13.1459V .