ANAPC10 explained
Anaphase-promoting complex subunit 10 is an enzyme that in humans is encoded by the ANAPC10 gene.[1] [2] [3]
Interactions
ANAPC10 has been shown to interact with CDC27,[4] [5] Mothers against decapentaplegic homolog 3[6] and Mothers against decapentaplegic homolog 2.[6]
Further reading
- Kurasawa Y, Todokoro K . Identification of human APC10/Doc1 as a subunit of anaphase promoting complex . Oncogene . 18 . 37 . 5131–7 . September 1999 . 10498862 . 10.1038/sj.onc.1203133 . 20373206 .
- Gotthardt M, Trommsdorff M, Nevitt MF, Shelton J, Richardson JA, Stockinger W, Nimpf J, Herz J . Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction . The Journal of Biological Chemistry . 275 . 33 . 25616–24 . August 2000 . 10827173 . 10.1074/jbc.M000955200 . free .
- Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM . The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex . Proceedings of the National Academy of Sciences of the United States of America . 97 . 16 . 8973–8 . August 2000 . 10922056 . 16806 . 10.1073/pnas.97.16.8973 . 2000PNAS...97.8973G . free .
- Wendt KS, Vodermaier HC, Jacob U, Gieffers C, Gmachl M, Peters JM, Huber R, Sondermann P . Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex . Nature Structural Biology . 8 . 9 . 784–8 . September 2001 . 11524682 . 10.1038/nsb0901-784 . 27021761 .
- Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM . TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 . Current Biology . 13 . 17 . 1459–68 . September 2003 . 12956947 . 10.1016/S0960-9822(03)00581-5 . 5942532 . free . 2003CBio...13.1459V .
- Nourry C, Maksumova L, Pang M, Liu X, Wang T . Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1 . BMC Cell Biology . 5 . 20 . May 2004 . 15144564 . 420458 . 10.1186/1471-2121-5-20 . free .
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M . Towards a proteome-scale map of the human protein-protein interaction network . Nature . 437 . 7062 . 1173–8 . October 2005 . 16189514 . 10.1038/nature04209 . 2005Natur.437.1173R . 4427026 .
Notes and References
- Grossberger R, Gieffers C, Zachariae W, Podtelejnikov AV, Schleiffer A, Nasmyth K, Mann M, Peters JM . Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex . The Journal of Biological Chemistry . 274 . 20 . 14500–7 . May 1999 . 10318877 . 10.1074/jbc.274.20.14500 . free .
- Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A . Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs . Genome Research . 11 . 3 . 422–35 . March 2001 . 11230166 . 311072 . 10.1101/gr.GR1547R .
- Web site: Entrez Gene: ANAPC10 anaphase promoting complex subunit 10.
- Vodermaier HC, Gieffers C, Maurer-Stroh S, Eisenhaber F, Peters JM . TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 . Current Biology . 13 . 17 . 1459–68 . September 2003 . 12956947 . 10.1016/S0960-9822(03)00581-5 . 5942532 . free . 2003CBio...13.1459V .
- Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM . The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex . Proceedings of the National Academy of Sciences of the United States of America . 97 . 16 . 8973–8 . August 2000 . 10922056 . 16806 . 10.1073/pnas.97.16.8973 . 2000PNAS...97.8973G . free .
- Nourry C, Maksumova L, Pang M, Liu X, Wang T . Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1 . BMC Cell Biology . 5 . 20 . May 2004 . 15144564 . 420458 . 10.1186/1471-2121-5-20 . free .