ALG10 explained

Alpha-1,2-glucosyltransferase ALG10-A is an enzyme that in humans is encoded by the ALG10 gene.[1] It is a member of the class of enzymes.

Function

This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.[2]

Notes and References

  1. UniProt ID: . Retrieved 30 November 2019
  2. Web site: Entrez Gene: ALG10 alpha-1,2-glucosyltransferase. 30 November 2019.