ALDH3B1 explained

Aldehyde dehydrogenase 3 family, member B1 also known as ALDH3B1 is an enzyme that in humans is encoded by the ALDH3B1 gene.[1] [2]

Function

The aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular gene spans about 20 kb of genomic DNA and is composed of 9 coding exons. The gene encodes a single transcript of 2.8 kb that is highly expressed in kidney and lung. The functional significance of this gene and the cellular localization of its product are presently unknown. Two transcript variants encoding different isoforms have been found for this gene.[3]

Further reading

Notes and References

  1. Hsu LC, Chang WC, Yoshida A . Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family . Gene . 151 . 1–2 . 285–9 . Dec 1994 . 7828891 . 10.1016/0378-1119(94)90672-6 .
  2. Hsu LC, Chang WC, Yoshida A . Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison . Gene . 189 . 1 . 89–94 . Apr 1997 . 9161417 . 10.1016/S0378-1119(96)00839-6 .
  3. Web site: Entrez Gene: ALDH3B1 .