AIM1 explained

Absent in melanoma 1 protein is a protein that in humans is encoded by the AIM1 gene.^{[1] [2] [3]}

External links

• • PDBe-KB provides an overview of all the structure information available in the PDB for Human Beta/gamma crystallin domain-containing protein 1 (AIM1)

Further reading

• Ray ME, Su YA, Meltzer PS, Trent JM . Isolation and characterization of genes associated with chromosome-6 mediated tumor suppression in human malignant melanoma. . Oncogene . 12 . 12 . 2527–33 . 1996 . 8700511 .
• Ray ME, Wistow G, Su YA . AIM1, a novel non-lens member of the betagamma-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma. . Proceedings of the National Academy of Sciences of the United States of America . 94 . 7 . 3229–34 . 1997 . 9096375 . 10.1073/pnas.94.7.3229 . 20351 . 1997PNAS...94.3229R . etal. free .
• Dias Neto E, Correa RG, Verjovski-Almeida S . Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. . Proceedings of the National Academy of Sciences of the United States of America . 97 . 7 . 3491–6 . 2000 . 10737800 . 10.1073/pnas.97.7.3491 . 16267 . 2000PNAS...97.3491D . etal. free .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proceedings of the National Academy of Sciences of the United States of America . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Mungall AJ, Palmer SA, Sims SK . The DNA sequence and analysis of human chromosome 6. . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . etal. free .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nature Genetics . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Aravind P, Rajini B, Sharma Y, Sankaranarayanan R . Crystallization and preliminary X-ray crystallographic investigations on a betagamma-crystallin domain of absent in melanoma 1 (AIM1), a protein from Homo sapiens. . Acta Crystallographica Section F . 62 . Pt 3 . 282–4 . 2006 . 16511323 . 10.1107/S1744309106005380 . 2197174 .

Notes and References

1. Millikin D, Meese E, Vogelstein B, Witkowski C, Trent J . Loss of heterozygosity for loci on the long arm of chromosome 6 in human malignant melanoma . Cancer Research . 51 . 20 . 5449–53 . Nov 1991 . 1680551 .
2. Rajini B, Graham C, Wistow G, Sharma Y . Stability, homodimerization, and calcium-binding properties of a single, variant betagamma-crystallin domain of the protein absent in melanoma 1 (AIM1) . Biochemistry . 42 . 15 . 4552–9 . Apr 2003 . 12693952 . 10.1021/bi027384l .
3. Web site: Entrez Gene: AIM1 absent in melanoma 1.