AHCYL1 explained

Putative adenosylhomocysteinase 2 is an enzyme that in humans is encoded by the AHCYL1 gene.^{[1] [2] [3] [4]}

Interactions

AHCYL1 has been shown to interact with ITPR1.

Further reading

• Pawlak A, Toussaint C, Lévy I . Characterization of a large population of mRNAs from human testis. . Genomics . 26 . 1 . 151–8 . 1995 . 7782076 . 10.1016/0888-7543(95)80096-5 . etal.
• Andersson B, Wentland MA, Ricafrente JY . A "double adaptor" method for improved shotgun library construction. . Anal. Biochem. . 236 . 1 . 107–13 . 1996 . 8619474 . 10.1006/abio.1996.0138 . etal.
• Yu W, Andersson B, Worley KC . Large-scale concatenation cDNA sequencing. . Genome Res. . 7 . 4 . 353–8 . 1997 . 9110174 . 10.1101/gr.7.4.353. 139146 . etal.
• Cleaver JE, Afzal V, Feeney L . Increased ultraviolet sensitivity and chromosomal instability related to P53 function in the xeroderma pigmentosum variant. . Cancer Res. . 59 . 5 . 1102–8 . 1999 . 10070969 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . etal . 2002PNAS...9916899M. free .
• Imabayashi H, Mori T, Gojo S . Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis. . Exp. Cell Res. . 288 . 1 . 35–50 . 2003 . 12878157 . 10.1016/S0014-4827(03)00130-7 . etal.
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Zhang Y, Wolf-Yadlin A, Ross PL . Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. . Mol. Cell. Proteomics . 4 . 9 . 1240–50 . 2005 . 15951569 . 10.1074/mcp.M500089-MCP200 . etal. free .
• Gregory SG, Barlow KF, McLay KE . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . etal. 2006Natur.441..315G . free .
• Shirakabe K, Priori G, Yamada H . IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1). . Proc. Natl. Acad. Sci. U.S.A. . 103 . 25 . 9542–7 . 2006 . 16769890 . 10.1073/pnas.0602250103 . 1480443 . etal. free .

Notes and References

1. Dekker JW, Budhia S, Angel NZ, Cooper BJ, Clark GJ, Hart DN, Kato M . Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation . Immunogenetics . 53 . 12 . 993–1001 . Mar 2002 . 11904675 . 10.1007/s00251-001-0402-z . 21593928 .
2. Cooper BJ, Key B, Carter A, Angel NZ, Hart DN, Kato M . Suppression and overexpression of adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling . J Biol Chem . 281 . 32 . 22471–84 . Aug 2006 . 16754674 . 10.1074/jbc.M602520200 . free .
3. Ando H, Mizutani A, Matsu-ura T, Mikoshiba K . IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor . J Biol Chem . 278 . 12 . 10602–12 . Mar 2003 . 12525476 . 10.1074/jbc.M210119200 . free .
4. Web site: Entrez Gene: AHCYL1 S-adenosylhomocysteine hydrolase-like 1.