ADP-ribose 1''-phosphate phosphatase explained

ADP-ribose 1′′-phosphate phosphatase
Ec Number:	3.1.3.84

ADP-ribose 1′′-phosphate phosphatase (EC 3.1.3.84, POA1, Appr1p phosphatase, Poa1p) is an enzyme with systematic name ADP-D-ribose 1′′-phosphate phosphohydrolase.^[1] This enzyme catalyses the following chemical reaction

ADP-D-ribose 1′′-phosphate + H₂O

\rightleftharpoons

ADP-D-ribose + phosphate

The enzyme is highly specific for ADP-ribose 1′′-phosphate.

Notes and References

Shull NP, Spinelli SL, Phizicky EM . A highly specific phosphatase that acts on ADP-ribose 1′′-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae . Nucleic Acids Research . 33 . 2 . 650–60 . 2005 . 15684411 . 548356 . 10.1093/nar/gki211 .