| ACS Medicinal Chemistry Letters | |
| Editor: | Dennis C. Liotta |
| Discipline: | Medicinal chemistry |
| Abbreviation: | ACS Med. Chem. Lett. |
| Publisher: | American Chemical Society |
| Country: | United States |
| Frequency: | Monthly |
| History: | 2009–present |
| Openaccess: | Hybrid |
| Impact: | 4.632 |
| Impact-Year: | 2021 |
| Website: | http://pubs.acs.org/journal/amclct |
| Link1: | https://pubs.acs.org/toc/amclct/current |
| Link1-Name: | Online access |
| Link2: | https://pubs.acs.org/loi/amclct |
| Link2-Name: | Online archive |
| Oclc: | 455500725 |
| Lccn: | 2009200243 |
| Coden: | AMCLCT |
| Eissn: | 1948-5875 |
ACS Medicinal Chemistry Letters is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University).
According to the Journal Citation Reports, the journal has a 2021 impact factor of 4.632.[1]