ACOT12 explained

Acyl-coenzyme A thioesterase 12 or StAR-related lipid transfer protein 15 (STARD15) is an enzyme that in humans is encoded by the ACOT12 gene.^{[1] [2] [3]} The protein contains a StAR-related lipid transfer domain.

External links

• • PDBe-KB provides an overview of all the structure information available in the PDB for Human Acetyl-coenzyme A thioesterase

Further reading

• Suematsu N, Isohashi F . Molecular cloning and functional expression of human cytosolic acetyl-CoA hydrolase. . Acta Biochim. Pol. . 53 . 3 . 553–61 . 2007 . 16951743 . 10.18388/abp.2006_3327. free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Suematsu N, Okamoto K, Isohashi F . Simple and unique purification by size-exclusion chromatography for an oligomeric enzyme, rat liver cytosolic acetyl-coenzyme A hydrolase. . J. Chromatogr. B . 790 . 1–2 . 239–44 . 2004 . 12767336 . 10.1016/s1570-0232(03)00167-3.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Suematsu N, Okamoto K, Shibata K . Molecular cloning and functional expression of rat liver cytosolic acetyl-CoA hydrolase. . Eur. J. Biochem. . 268 . 9 . 2700–9 . 2001 . 11322891 . 10.1046/j.1432-1327.2001.02162.x . etal. free .

Notes and References

1. Hunt MC, Yamada J, Maltais LJ, Wright MW, Podesta EJ, Alexson SE . A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases . J Lipid Res . 46 . 9 . 2029–32 . Aug 2005 . 16103133 . 10.1194/jlr.E500003-JLR200 . free .
2. Hunt MC, Rautanen A, Westin MA, Svensson LT, Alexson SE . Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs . FASEB J . 20 . 11 . 1855–64 . Aug 2006 . 16940157 . 10.1096/fj.06-6042com . free . 501610 .
3. Web site: Entrez Gene: ACOT12 acyl-CoA thioesterase 12.