ACER3 explained

Alkaline ceramidase 3 also known as ACER3 is a ceramidase enzyme which in humans is encoded by the ACER3 gene.^{[1] [2]}

Further reading

• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Wheeler HE, Metter EJ, Tanaka T . Gibson . Greg . Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. . PLOS Genet. . 5 . 10 . e1000685 . 2009 . 19834535 . 10.1371/journal.pgen.1000685 . 2752811 . etal . free .

Notes and References

1. Mao C, Xu R, Szulc ZM, Bielawska A, Galadari SH, Obeid LM . Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide . J. Biol. Chem. . 276 . 28 . 26577–88 . July 2001 . 11356846 . 10.1074/jbc.M102818200 . free .
2. Mao C, Obeid LM . Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate . Biochim. Biophys. Acta . 1781 . 9 . 424–34 . September 2008 . 18619555 . 10.1016/j.bbalip.2008.06.002 . 2614331 .