ABT-202 explained

ABT-202 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors and has been researched for use as an analgesic, although it has not passed clinical trials.[1] [2] [3]

Notes and References

  1. Jain KK . Modulators of nicotinic acetylcholine receptors as analgesics . Current Opinion in Investigational Drugs . 5 . 1 . 76–81 . January 2004 . 14983978 .
  2. Romanelli MN, Gratteri P, Guandalini L, Martini E, Bonaccini C, Gualtieri F . Central nicotinic receptors: structure, function, ligands, and therapeutic potential . ChemMedChem . 2 . 6 . 746–67 . June 2007 . 17295372 . 10.1002/cmdc.200600207 . 34763474 .
  3. Xu N, Kim GE, Gregg H, Wagdy A, Swaine BA, Chang MS, El-Shourbagy TA . Automated 96-well liquid-liquid back extraction liquid chromatography-tandem mass spectrometry method for the determination of ABT-202 in human plasma . Journal of Pharmaceutical and Biomedical Analysis . 36 . 1 . 189–95 . September 2004 . 15351065 . 10.1016/j.jpba.2004.05.013 .

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