| Country: | FRA |
| Type: | A |
| Route: | 49 |
| Alternate Name: | |
| Map: | France A4X A49.svg |
| Length Km: | 70.4 |
| Established: | 1992 |
| Direction A: | West |
| Direction B: | East |
| Terminus B: | Grenoble |
The A49 autoroute is a motorway in France. The road provides a connection between Romans (Valence) with Grenoble.
The first section was opened in 1991 between the junction with the A48 towards Voreppe and the junction at Tullins (N°11). Its extension to Romans-sur-Isère was opened in 1992.
| Exit/Junction | Destination | |
| Exchange A48-A49 Junction with to Lyon and Grenoble | ||
| (Tullins) Towns served: Tullins | ||
| (Vinay) Towns served: Vinay | ||
| (Saint-Marcelin) Towns served: Saint-Marcelin | ||
| (Saint-Nazaire-en-Royans) Towns served: Saint-Nazaire-en-Royans | ||
| (Novel-de-Isere) Towns served: Romans-sur-Isere | ||
| (Bourg-de-Péage) Towns served: Romans-sur-Isere, Bourg-de-Péage | ||
| The A49 becomes the and remains dual carriageway | ||
| (Les Soubres) | ||
| (Valance TGV) | ||
| (St-Marcel-lès-Valence) | ||
| (Le Plovier) | ||
| Exchange N532-N7 Road joins the Valence western bypass to the | ||