Rs1800532 Explained

Rsid:1800532
Name 1:A218C
Region:Intron 7
Gene:TPH1
Chromosome:11

In genetics, rs1800532 (A218C) is a genetic variant.It is a single nucleotide polymorphism in the TPH1 gene and located in intron 7.

It has been examined in relation to personality traits.[1] [2] [3]

A779C is another SNP in same intron.

Notes and References

  1. . Allelic variants of the tryptophan hydroxylase (A218C) and serotonin 1B receptor (A-161T) and personality traits . . 48 . 2 . 68–71 . 2003 . 10.1159/000072879 . 14504413. 42559772 .
  2. . The TPH intron 7 A218C polymorphism and TCI dimension scores in alcohol-dependent patients: hints to nonspecific psychopathology . . 30 . 6 . 1135–43 . July 2005 . 10.1016/j.addbeh.2004.11.002 . 15925123.
  3. . No association between the TPH A218C polymorphism and personality traits in Japanese healthy subjects . . 31 . 2 . 395–398 . March 2007 . 10.1016/j.pnpbp.2006.10.003 . 17116352. 30569509 .