| Country: | RUS |
| Type: | A |
| Route: | 164 |
| Alternate Name: | Transkam Highway |
| Length Km: | 164 |
| Direction A: | North |
| Terminus A: | in Kardzhin |
| Direction B: | South |
| Terminus B: | Georgian border |
| Previous Type: | A |
| Previous Route: | 163 |
| Next Type: | A |
| Next Route: | 165 |
The Russian route A164, also known as Transkam Highway, is a Russian federal highway. A164 highway is a part of Transcaucasian Highway, connecting southern Russia and Georgia. Before 2018, the route was designated R297 and R298.
The A164 designation was used on a route from Kultuk via Mondy to the Mongolian border. This route is now A333.