A-372159 Explained

A-372159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM. It has been found to produce anorectic effects in animal studies and produced significant weight loss in rats with no development of tolerance or serious side effects.[1]

Notes and References

  1. Childers WE, Robichaud AJ . Recent advances in selective serotonergic agents. . Annual Reports in Medicinal Chemistry . January 2005 . 40 . 17–33 . 10.1016/S0065-7743(05)40002-0 . 978-0-12-040540-4 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "A-372159".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.