9,12-octadecadienoate 8-hydroperoxide 8S-isomerase explained
| 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase |
| Ec Number: | 5.4.4.6 |
9,12-octadecadienoate 8-hydroperoxide 8S-isomerase (8-hydroperoxide isomerase, (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-7,8-dihydroxy-9,12-octadecadienoate-forming)) is an enzyme with systematic name (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate hydroxymutase ((7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate-forming).[1] [2] [3] This enzyme catalyses the following chemical reaction
(8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate
(7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate
This enzyme contains heme.
Notes and References
- Hamberg M, Zhang LY, Brodowsky ID, Oliw EH . Sequential oxygenation of linoleic acid in the fungus Gaeumannomyces graminis: stereochemistry of dioxygenase and hydroperoxide isomerase reactions . Archives of Biochemistry and Biophysics . 309 . 1 . 77–80 . February 1994 . 8117115 . 10.1006/abbi.1994.1087 .
- Su C, Sahlin M, Oliw EH . A protein radical and ferryl intermediates are generated by linoleate diol synthase, a ferric hemeprotein with dioxygenase and hydroperoxide isomerase activities . The Journal of Biological Chemistry . 273 . 33 . 20744–51 . August 1998 . 9694817 . 10.1074/jbc.273.33.20744 . free .
- Su C, Oliw EH . Purification and characterization of linoleate 8-dioxygenase from the fungus Gaeumannomyces graminis as a novel hemoprotein . The Journal of Biological Chemistry . 271 . 24 . 14112–8 . June 1996 . 8662736 . 10.1074/jbc.271.24.14112 . free .
