8-Cyclopentyl-1,3-dimethylxanthine explained

8-Cyclopentyl-1,3-dimethylxanthine (8-Cyclopentyltheophylline, 8-CPT, CPX) is a drug which acts as a potent and selective antagonist for the adenosine receptors, with some selectivity for the A₁ receptor subtype, as well as a non-selective phosphodiesterase inhibitor. It has stimulant effects in animals with slightly higher potency than caffeine.^{[1] [2]}

See also

• 8-Chlorotheophylline
• 8-Phenyltheophylline
• DMPX
• DPCPX
• Xanthine

Notes and References

1. Spealman RD . Psychomotor stimulant effects of methylxanthines in squirrel monkeys: relation to adenosine antagonism . Psychopharmacology . 95 . 1 . 19–24 . 1988 . 3133696 . 10.1007/bf00212759 . 11539292 .
2. Karcz-Kubicha M, Antoniou K, Terasmaa A, Quarta D, Solinas M, Justinova Z, Pezzola A, Reggio R, Müller CE, Fuxe K, Goldberg SR, Popoli P, Ferré S . 6 . Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration . Neuropsychopharmacology . 28 . 7 . 1281–91 . July 2003 . 12700682 . 10.1038/sj.npp.1300167 . free .