8-Bromotheophylline Explained
| Drug Name: | 8-Bromotheophylline |
| Width: | 180 |
| Cas Number: | 10381-75-6 |
| Pubchem: | 11808 |
| Drugbank: | DB14018 |
| Chemspiderid: | 11315 |
| Unii: | FZG87K1MQ6 |
| Chembl: | 316160 |
| Dtxsid: | DTXSID7044768 |
| Synonyms: | Bromotheophylline |
| Iupac Name: | 8-Bromo-1,3-dimethyl-7H-purine-2,6-dione |
| C: | 7 |
| H: | 7 |
| Br: | 1 |
| N: | 4 |
| O: | 2 |
| Smiles: | CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Br |
| Stdinchi: | 1S/C7H7BrN4O2/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h1-2H3,(H,9,10) |
| Stdinchikey: | SKTFQHRVFFOHTQ-UHFFFAOYSA-N |
8-Bromotheophylline is a xanthine diuretic drug. It is the main active ingredient in pamabrom where it is sold as an over-the-counter medication in combination with paracetamol, among other analgesics, to treat dysmenorrhea.[1] [2] It is also an adenosine receptor A1 antagonist.[3]
See also
Notes and References
- Ortiz MI, Murguía-Cánovas G, Vargas-López LC, Silva R, González-de la Parra M . Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial . Medwave . 16 . 9 . e6587 . October 2016 . 27813503 . 10.5867/medwave.2016.09.6587 . free .
- Ortiz MI . Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment . European Journal of Obstetrics, Gynecology, and Reproductive Biology . 152 . 1 . 73–77 . September 2010 . 20478651 . 10.1016/j.ejogrb.2010.04.015 .
- Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W . 6 . Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors . Journal of Medicinal Chemistry . 36 . 18 . 2639–2644 . September 1993 . 8410976 . 10.1021/jm00070a007 .
