7-Dimethylallyltryptophan synthase explained

7-dimethylallyltryptophan synthase
Ec Number:	2.5.1.80

7-dimethylallyltryptophan synthase (7-DMATS) is an enzyme with systematic name dimethylallyl-diphosphate:L-tryptophan 7-dimethylallyltransferase.^{[1] [2]} This enzyme catalyses the following chemical reaction:

\rightleftharpoons diphosphate + 7-(3-methylbut-2-enyl)-L-tryptophan

This enzyme is more flexible towards the aromatic substrate than EC 2.5.1.34 (4-dimethylallyltryptophan synthase).

Notes and References

1. Kremer A, Li SM . Potential of a 7-dimethylallyltryptophan synthase as a tool for production of prenylated indole derivatives . Applied Microbiology and Biotechnology . 79 . 6 . 951–61 . July 2008 . 18481055 . 10.1007/s00253-008-1505-3 .
2. Kremer A, Westrich L, Li SM . A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization . Microbiology . 153 . Pt 10 . 3409–16 . October 2007 . 17906140 . 10.1099/mic.0.2007/009019-0 .