7α-Hydroxycholesterol explained

7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase (CYP7A1). Its formation is the rate-determining step in bile acid synthesis.[1]

Notes and References

  1. Chiang JY, Ferrell JM . Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy . American Journal of Physiology. Gastrointestinal and Liver Physiology . 318 . 3 . G554–G573 . March 2020 . 31984784 . 7099488 . 10.1152/ajpgi.00223.2019 .

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