60S ribosomal protein L34 explained

60S ribosomal protein L34 is a protein that in humans is encoded by the RPL34 gene.[1] [2] [3]

Function

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.[3]

Further reading

External links

Notes and References

  1. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC . A map of 75 human ribosomal protein genes . Genome Research . 8 . 5 . 509–23 . May 1998 . 9582194 . 10.1101/gr.8.5.509 . free .
  2. Rommens JM, Durocher F, McArthur J, Tonin P, LeBlanc JF, Allen T, Samson C, Ferri L, Narod S, Morgan K . Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21 . Genomics . 28 . 3 . 530–42 . August 1995 . 7490091 . 10.1006/geno.1995.1185 .
  3. Web site: Entrez Gene: RPL34 ribosomal protein L34.