6-aminohexanoate-dimer hydrolase explained

6-aminohexanoate-dimer hydrolase
Ec Number:	3.5.1.46
Cas Number:	75216-15-8
Go Code:	0019875

In enzymology, a 6-aminohexanoate-dimer hydrolase is an enzyme that catalyzes the chemical reaction N-(6-aminohexanoyl)-6-aminohexanoate + H₂O

\rightleftharpoons 2 6-aminohexanoate. Thus, the two substrates of this enzyme are N-(6-aminohexanoyl)-6-aminohexanoate and H₂O, whereas its product is two molecules of 6-aminohexanoate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase. This enzyme is also called 6-aminohexanoic acid oligomer hydrolase.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes,, and .

See also

• Nylon-eating bacteria

References

• Kinoshita S, Terada T, Taniguchi T, Takene Y, Masuda S, Matsunaga N, Okada H . Purification and characterization of 6-aminohexanoic-acid-oligomer hydrolase of Flavobacterium sp. Ki72 . European Journal of Biochemistry . 116 . 3 . 547–51 . June 1981 . 7262074 . 10.1111/j.1432-1033.1981.tb05371.x . free .