6-CAT explained

6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.[1] [2] It is a rigid analogue of para-chloroamphetamine (PCA).[1]

According to Nichols et al.,[3] 6-CAT is a non-neurotoxic analog of PCA.

See also

Notes and References

  1. Fuller RW, Perry KW, Baker JC, Molloy BB . 6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats . Archives Internationales de Pharmacodynamie et de Therapie . 212 . 1 . 141–53 . November 1974 . 4455127 .
  2. Fuller RW, Wong DT, Snoddy HD, Bymaster FP . Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats . Biochemical Pharmacology . 26 . 1 . 1,333–1,337 . 1977 . 10.1016/0006-2952(77)90094-6.
  3. Johnson MP, Frescas SP, Oberlender R, Nichols DE . Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA) . Journal of Medicinal Chemistry . 34 . 5 . 1662–8 . May 1991 . 1674539 . 10.1021/jm00109a020 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "6-CAT".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.