6-(2-Aminopropyl)indole explained
| Iupac Name: | 1-(1H-Indol-6-yl)propan-2-amine |
| Legal De: | Uncontrolled |
| Legal Status: | Uncontrolled (but covered under the Federal Analogue Act in the United States and Australia and likely under similar bills in other countries) |
| Routes Of Administration: | Oral |
| Cas Number: | 22196-72-1 |
| Unii: | M7C77J017A |
| Pubchem: | 30999 |
| Chemspiderid: | 28759 |
| C: | 11 |
| H: | 14 |
| N: | 2 |
| Smiles: | C1=C2C(=CC=C1CC(C)N([H])[H])C=C[N]2[H] |
| Stdinchi: | 1S/C11H14N2/c1-8(12)6-9-2-3-10-4-5-13-11(10)7-9/h2-5,7-8,13H,6,12H2,1H3 |
| Stdinchikey: | QCFIFKAOUKPFPU-UHFFFAOYSA-N |
6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative which was first identified being sold on the designer drug market by a laboratory in the Czechia in July 2016.[1]
Alexander Shulgin says in his book TiHKAL "From the normal 3-position to the 2, the 4, the 5, the 6 or the 7-positions. All five alpha-methyltryptamine isomers are known, but only one is known to be active in man as a CNS active material. This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT"http://www.erowid.org/library/books_online/tihkal/tihkal48.shtml.
Studies in dogs have also shown the drug to increase hemoglobin levels in the bloodstream.[2]
Legality
- 6-API is a positional isomer of αMT, and as such may be covered by the analogue act in the USA (depending on the nature of its psychoactive effect).
- 6-API / 6-IT is illegal in the UK, as it was banned as a temporary class drug in June 2013, along with 9 other related compounds.[3] On March 5, 2014, the UK Home Office announced that 6-API would be made a class B drug on 10 June 2014 alongside every other benzofuran entactogen and many structurally related drugs.[4]
- 6-API is covered by the Australian analogue act as an analogue of MDA "by the replacement of up to 2 carbocyclic or heterocyclic ring structures with different carbocyclic or heterocyclic ring structures"[5]
- 6-API is uncontrolled in Germany, as indole rings are not included as rings under the 2-phenethylamine derived section of the NPsG.[6]
Notes and References
- http://www.emcdda.europa.eu/system/files/publications/4724/TDAN17001ENN_PDFWEB.pdf Europol 2016 Annual Report on the implementation of Council Decision 2005/387/JHA
- Maxwell GM . The effects of an indole derivative 692'-amino-propyl indole) on the general and coronary haemodynamics of the intact dog . Experientia . 20 . 9 . 526–7 . September 1964 . 5856353 . 10.1007/BF02154095 . 7574163 .
- Web site: Temporary class drug order report on 5-6APB and NBOMe compounds . 2013-07-11 . 4 Jun 2013 . UK Home Office.
- Web site: The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 . 2014-03-11 . UK Home Office . 2014-03-05 . UK Government.
- Web site: Criminal Code Act 1995 . 2012-02-08 . 2009-08-05 . Australian Government . PAGE 503.
- Web site: New Psychoactive Substances Act (Neue-psychoaktive-Stoffe-Gesetz) (NpSG) Non-official translation. 9 November 2021.
