6,6-Difluoronorethisterone Explained

6,6-Difluoronorethisterone, also known as 6,6-difluoro-17α-ethynyl-19-nortestosterone or as 6,6-difluoro-17α-ethynylestr-4-en-17β-ol-3-one, is a steroidal progestin of the 19-nortestosterone group that was described in 1971 but was never marketed.^{[1] [2] [3]} It is a fluorinated derivative of norethisterone. The C17β acetate ester, 6,6-difluoronorethisterone acetate, has also been synthesized and described.

Notes and References

1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 522–.
2. Book: Overton KH . Terpenoids and Steroids. January 1973. Royal Society of Chemistry. 978-0-85186-276-7. 432–.
3. Book: Morrow DF, Gallo D . Steroids and Biologically Related Compounds. . Pachter I . Annual Reports in Medicinal Chemistry . January 1972 . 7 . 182-193 (187) . Academic Press . https://books.google.com/books?id=52joNWUvZakC&pg=PA187 . 978-0-08-058351-8 .