6β-Naltrexol-d4 explained

6β-Naltrexol-d4, also known as 6β-hydroxynaltrexone-d4, is a deuterium-labeled form of 6β-naltrexol used for NMR imaging. Unlike opioid inverse agonists such as naloxone and naltrexone (which are often dubbed "antagonists" for simplicity's sake), 6β-naltrexol and 6β-naltrexol-d4 are opioid neutral antagonists.[1]

Notes and References

  1. Sirohi S, Dighe SV, Madia PA, Yoburn BC . The relative potency of inverse opioid agonists and a neutral opioid antagonist in precipitated withdrawal and antagonism of analgesia and toxicity . The Journal of Pharmacology and Experimental Therapeutics . 330 . 2 . 513–9 . August 2009 . 19435929 . 2713087 . 10.1124/jpet.109.152678 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "6β-Naltrexol-d4".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.