MDMAT explained

MDMAT (6,7-methylenedioxy-N-methyl-2-aminotetralin) is a selective serotonin releasing agent (SSRA) and entactogen drug. It is the N-methylated derivative of MDAT, similarly to the relationship of MDMA to MDA.^{[1] [2]} It has been theorized to have less long-term neurotoxicity and less hallucinogenic effects than other MDxx derivatives,^[3] but no formal scientific research has been conducted specifically on MDMAT.

There is a lack of research on MDMAT in general, with much of the research and citation in literature being in reference to the wider pharmalogical/chemical class as a whole.

Chemistry

MDMAT is a substituted methylenedioxyphenethylamine, having structural similarities to MDMA and MDA.

See also

• 2-Aminotetralin
• Substituted methylenedioxyphenethylamine

Notes and References

1. Potential psychotropic compounds. VIII. Synthesis and pharmacological activity of 2-aminotetralins related to psychomimetics . Violland R, Violland-Duperret N, Pacheco H, Trouiller G, Lebland A . Chimica Therapeutica . 1971 . 6 . 3 . 196.
2. Malmusi L, Dukat M, Young R, Teitler M, Darmani NA, Ahmad B, Smith C, Glennon RA . 1,2,3,4-Tetrahydroisoquinoline and related analogs of the phenylalkylamine designer drug MDMA. . Medicinal Chemistry Research . January 1996 . 6 . 6 . 412–26m .
3. Nichols DE, Brewster WK, Johnson MP, Oberlender R, Riggs RM . Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA) . Journal of Medicinal Chemistry . 33 . 2 . 703–710 . February 1990 . 1967651 . 10.1021/jm00164a037 .