MDAT explained

Iupac Name:5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxol-6-amine
Legal Status:Uncontrolled
Routes Of Administration:Oral
Index2 Label:hydrochloride
Cas Number:101625-35-8
Cas Number2:3446-21-8
Unii:28IR5LC41Q
Unii2:BOX4U52EET
Atc Prefix:none
Pubchem:36483
Chemspiderid:33531
C:11
H:13
N:1
O:2
Smiles:C3Cc1cc2OCOc2cc1CC3N

6,7-Methylenedioxy-2-aminotetralin (MDAT) is a drug developed in the 1990s by a team at Purdue University led by David E. Nichols.[1] It appears to act as a serotonin releasing agent based on rodent drug discrimination assays comparing it to MDMA, in which it fully substitutes for, and additionally lacks any kind of serotonergic neurotoxicity.[1] Hence, MDAT is considered likely to be a non-neurotoxic, putative entactogen in humans.

See also

Notes and References

  1. Nichols DE, Brewster WK, Johnson MP, Oberlender R, Riggs RM . Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA) . Journal of Medicinal Chemistry . 33 . 2 . 703–10 . February 1990 . 1967651 . 10.1021/jm00164a037.