5-Hydroxyisourate Explained

5-Hydroxyisourate is an organic compound that is produced by the oxidation of uric acid. The conversion is a major pathway in the antioxidant properties of urate. The conversion is catalysed by urate oxidase.[1] [2] 5-Hydroxyisourate rearranges to allantoin.

See also

Notes and References

  1. Oksanen E, Blakeley MP, El-Hajji M, Ryde U, Budayova-Spano M . The Neutron Structure of Urate Oxidase Resolves a Long-Standing Mechanistic Conundrum and Reveals Unexpected Changes in Protonation . PLOS ONE . 9 . 1 . e86651 . 2014-01-23 . 24466188 . 3900588 . 10.1371/journal.pone.0086651 . 2014PLoSO...986651O . free .
  2. 10.1007/s00253-010-2455-0. Cofactor-independent oxidases and oxygenases . 2010 . Fetzner . Susanne . Steiner . Roberto A. . Applied Microbiology and Biotechnology . 86 . 3 . 791–804 . 20157809 . 25377247 .

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