| 5-amino-6-(5-phosphoribosylamino)uracil reductase | |
| Ec Number: | 1.1.1.193 |
| Cas Number: | 69020-28-6 |
| Go Code: | 0008703 |
In enzymology, a 5-amino-6-(5-phosphoribosylamino)uracil reductase is an enzyme that catalyzes the chemical reaction
5-amino-6-(5-phosphoribitylamino)uracil + NADP+
\rightleftharpoons
Thus, the two substrates of this enzyme are 5-amino-6-(5-phosphoribitylamino)uracil and NADP+, whereas its 3 products are 5-amino-6-(5-phosphoribosylamino)uracil, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase. This enzyme is also called aminodioxyphosphoribosylaminopyrimidine reductase. This enzyme participates in riboflavin metabolism.
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and .