5α-Androst-2-ene-17-one explained

5α-Androst-2-en-17-one is an endogenous, naturally occurring, orally active anabolic-androgenic steroid (AAS) and a derivative of dihydrotestosterone (DHT). It is a metabolite of dehydroepiandrosterone (DHEA) in the body[1] [2] and is also a pheromone found in elephants and boars.[3] 5α-Androst-2-en-17-one has been sold on the Internet as a "dietary supplement". It resembles desoxymethyltestosterone (17α-methyl-5α-androst-2-en-17β-ol) in chemical structure and may act as an androgen prohormone.

Notes and References

  1. Callies F, Arlt W, Siekmann L, Hübler D, Bidlingmaier F, Allolio B . 2630118 . Influence of oral dehydroepiandrosterone (DHEA) on urinary steroid metabolites in males and females . Steroids . 65 . 2 . 98–102 . February 2000 . 10639021 . 10.1016/S0039-128X(99)00090-2 .
  2. Gower DB, Mallet AI, Watkins WJ, Wallace LM . Transformations of steroid sulphates by human axillary bacteria. A mechanism for human odour formation? . Biochemical Society Transactions . 25 . 1 . 16S . February 1997 . 9056914 . 10.1042/bst025016s .
  3. Book: Marchlewska-Koj A, Lepri JJ, Müller-Schwarze D . 2001 . Chemical signals in vertebrates 9 . Springer . 9 . 131 . 978-0-306-46682-3 .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "5α-Androst-2-ene-17-one".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.