5''-phosphoribostamycin phosphatase explained

5′′-phosphoribostamycin phosphatase
Ec Number:	3.1.3.88

5′′-phosphoribostamycin phosphatase (EC 3.1.3.88) is an enzyme with systematic name 5′′-phosphoribostamycin phosphohydrolase.^[1] This enzyme catalyses the following chemical reaction

5′′-phosphoribostamycin + H₂O

\rightleftharpoons ribostamycin + phosphate

This enzyme is involved in the biosynthesis of several aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin.

Notes and References

1. Kudo F, Fujii T, Kinoshita S, Eguchi T . Unique O-ribosylation in the biosynthesis of butirosin . Bioorganic & Medicinal Chemistry . 15 . 13 . 4360–8 . July 2007 . 17482823 . 10.1016/j.bmc.2007.04.040 .