| 49ers–Rams rivalry | |
| Team1: | San Francisco 49ers |
| Team2: | Los Angeles Rams |
| Team1logo: | San Francisco 49ers Saloon Wordmark.svg |
| Team2logo: | LA Rams wordmark.svg |
| First Contested: | October 1, 1950 Rams 35, 49ers 14 |
| Mostrecent: | January 7, 2024 Rams 21, 49ers 20 |
| Nextmeeting: | September 22, 2024 |
| Total: | 150 |
| Largestvictory: | Rams, 56–7 (1958) 49ers, 48–0 (1987) |
| Currentstreak: | Rams, 1 (2023–present) |
| Section Header: | Championship Success |
| Section Info: | NFL Championships (9)
Super Bowls won:
NFC Championships (13): |
| Longeststreak: | 49ers, 17 (1990–1998) Rams, 10 (1970–1975) |
| Series: | 49ers, 78–69–3 |
| Postseason: | Tie, 1–1 |
The 49ers–Rams rivalry is a rivalry between the San Francisco 49ers and the Los Angeles Rams of the National Football League (NFL). The rivalry began in and became one of the most intense in the NFL in the 1970s as the two California based teams regularly competed for the NFC West Division title. During the mid-2010s and 2020s, the rivalry returned to the same intensity following the Rams’ return to Los Angeles and subsequent playoff success. Geography plays a strong role in animosity between the two teams as Northern California (where the 49ers are based) and Southern California (where the Rams are based) have long been competitors in the economic, cultural, and political arenas. Similarly to the Dodgers–Giants rivalry equivalent in baseball, the Kings–Sharks rivalry equivalent in hockey, the Lakers–Warriors rivalry equivalent in basketball, and the California Clásico equivalent in soccer, animosity between the two has led to acts of violence or public disdain between fans, players, or coaches alike.
During the Rams' 20-season tenure in St. Louis, the rivalry did not have the geographical lore it once had, but the games were still intense regardless of the standings. With the Rams’ return to Los Angeles in 2016, the rivalry became geographic once again. Sports Illustrated considers their rivalry the 8th best of all time in the NFL.[1] The 49ers and Rams are also the only two teams who have been a part of the NFC West since it was formed in .
The Rams, who dominated much of the first 30 years of the rivalry, led the series by as many as 22 games in, but the 49ers' strong play in the 1980s and 1990s, including a 17–game winning streak from – allowed them to take the lead. The teams have met twice in the NFL playoffs, once in the 1989 NFC Championship Game with a 30–3 49ers victory and again in the 2021 NFC Championship Game with a 20–17 Rams victory.
In 1950, the National Football League merged with the All-America Football Conference thus gaining three new teams. One of these teams was the San Francisco 49ers making them the second NFL franchise located on the West Coast, the first one being the Los Angeles Rams who had re-located from Cleveland in 1946. The NFL placed both of them in the newly formed National Conference (1950–52) guaranteeing that they would play each other twice during the regular season. In 1953, the National Conference was renamed the Western Conference and the American Conference was renamed the Eastern Conference which remained in place until the AFL merger forced re-alignment in 1970. For the 1967, 1968, and 1969 seasons immediately preceding the 1970 re-alignment, now with 16 franchises, the NFL divided the Western and Eastern Conferences into two Divisions of four teams each, ironically very similar to the present-day conferences resulting from the 2002 re-alignment. The 49ers and Rams remained together in the Coastal Division of the Western Conference (1967–1969) and then in the NFC West Division since 1970. Owing to the strength of their rivalry, the 49ers and Rams have remained in place as the only two teams in the NFC West Division continuously since 1970, despite the Rams' re-location to Saint Louis in 1995 and further re-alignment in 2002. They have met twice every season beginning in 1950. The teams have met twice in the NFL Playoffs. Their first postseason meeting was in the NFC Championship Game following the 1989 season at Candlestick Park in San Francisco. This resulted in a 30–3 victory by the 49ers on January 14, 1990, immediately preceding their fourth Super Bowl appearance. On January 30, 2022, they would again meet in the NFC Championship Game at Los Angeles' Sofi Stadium where the Rams would break a six-game losing skid to the 49ers, winning 20-17 en route a victory in Super Bowl LVI.
The first meeting between the teams took place on October 1, 1950, in San Francisco. The Rams were alternating starting quarterbacks between Bob Waterfield and Norm Van Brocklin during the 1950 season. Waterfield was the starter for the game, but during the second quarter, San Francisco's Pete Wissman landed a hard tackle on the Los Angeles quarterback. Van Brocklin filled in for Waterfield, and the Rams won the game 35–14.[2] The two teams played each other again on November 5, 1950, at the Los Angeles Memorial Coliseum in Los Angeles. After beating the Baltimore Colts 70–21 and the Detroit Lions 65–24, the Rams were favored to beat the 49ers by 20 points. Yet, the 49ers played a very physical game and only lost by a touchdown holding the Rams' offensive powerhouse to only 28 points.[3]
The 49ers got their first win against the Rams on October 28, 1951. The 49ers secondary was able to pick off Van Brocklin six times, more than half of the interceptions that he threw all season. The 49ers held the Rams to just 17 points, the lowest they put up all season, and were able to capitalize on the turnovers en route to a 44–17 victory.
The rivalry was almost even through the decade, with the Rams holding a 10-9-1 edge. The 49ers were also run throughout the 1960s, while the Rams did not contend until the arrival of coach George Allen in 1966. In 1967, the 49ers and Rams were placed in the Coastal Division of the NFL's Western Conference with the Atlanta Falcons (who remained a rival in the NFC West through 2001) and Baltimore Colts.
After the AFL-NFL merger, both teams were placed in the NFC West and were the only teams required to be in the same division by the merger agreement. The rivalry was at its pinnacle during the 1970s. From 1970 to 1979 one of the two teams won the division each season. The decade also featured 10 and 8-game win streaks by the Rams (the 8-game streak stretched into the early 1980s). The 49ers were the NFC West's top team in the beginning of the decade winning the first three post-merger division crowns despite going 1–5 in that period vs. the Rams. The Rams answered right back winning seven straight division crowns from 1973 to 1979, culminating with Super Bowl XIV loss to the Pittsburgh Steelers.
On January 2, 1983, a 1–7 Rams team met the 3–5 defending Super Bowl champion 49ers in San Francisco for the last game of the 1982 season (a players' strike shortened the season to 9 games), with the 49ers needing a win to make the playoffs. The Rams led late in the 4th quarter 21–20 until 49ers quarterback Joe Montana led a two-minute drive, putting the 49ers in position for a short field goal. But Ivory Sully blocked Ray Wersching's kick to preserve a 21–20 win and knock the 49ers out of the playoffs.[4]
On January 14, 1990, the two teams met in the 1989 NFC Championship game. The Rams were heavy underdogs but had already pulled off two upsets on the road in the playoffs (over the Eagles and Giants). The Rams took an early 3–0 lead and were driving again, but Rams quarterback Jim Everett noticed a wide-open Flipper Anderson a second too late, and the pass was knocked away by 49ers safety Ronnie Lott. Instead of a 10–0 Rams lead, Montana led the 49ers on a touchdown drive and San Francisco took the lead 7–3. The 49ers would win the game, 30–3.
The 49ers dominated the rivalry during the 1990s, winning 17 straight games against the Rams. They also won their fifth Super Bowl in . After nearly fifty years, it seemed like the rivalry was coming to an end when the Rams relocated to St. Louis in . Yet, some players did not believe so. Roger Craig stated in Tales from the San Francisco 49ers Sideline that "the Rams will always be the 49ers' biggest rival. It doesn't matter if they no longer play in Los Angeles. If the Rams played their home games on Mars, it would still be a rivalry."[5]
By the end of the season, San Francisco led in the all-time series (49–48–2) for the first time ever. The Rams previously led in the series by as many as 22 games in 1980. The 49ers' lead in the series was short-lived, however, as St. Louis won both games against San Francisco during their championship season in 1999 to retake the lead.
The Rams and their Greatest Show on Turf offense (1999-2001) regained the upper hand against San Francisco with 6 consecutive regular-season victories against them in that period right after having previously dropped 17 straight games including one playoff loss in the 1989 NFC Championship game. Ultimately, in the early 2000s, they went 8–2 against the 49ers from 2000 to 2004.[6] But both teams fell into decline and neither team was a playoff contender as the decade wore on. The 49ers had the upper hand during the latter part of the decade, going 8–2 against St. Louis from 2005 to 2009.
During the realignment, only the Rams and 49ers would remain in the NFC West, as their former division rivals, the Atlanta Falcons, Carolina Panthers, and New Orleans Saints, would all move to the newly formed NFC South. The Rams and 49ers would be joined by the Arizona Cardinals and Seattle Seahawks in the "new" NFC West.
In 2011, the 49ers took the all-time series lead for the first time in 13 years. The Rams tied it back up with a win at Edward Jones Dome in 2012, but then they lost both 2013 games to the 49ers.
In 2016, the Rams returned to Los Angeles, marking a restoration of the Bay Area-Los Angeles rivalry. San Francisco finished 25–16–1 against the Rams during their time in St. Louis.
The Rams were the only team to lose to the 49ers in 2016, as the 49ers swept the two-game series against the Rams but went 0–14 against the rest of the NFL. The two teams won one NFC championship each to close out the decade (Los Angeles in 2018, San Francisco in 2019), but neither team won the Super Bowl. In 2019, the second 49ers–Rams game was in Week 15; the Rams held an early 21–10 lead, but the 49ers came back, defeating Los Angeles 34–31 to knock the Rams out of playoff contention.[7]
The 49ers swept the Rams for the second straight season in, winning 24–16 on Sunday Night Football in Week 6, followed by a 23–20 victory in Week 12. It was the Rams' first-ever loss in their new venue SoFi Stadium. In, the 49ers again won both head-to-head meetings. This included the regular season finale in Los Angeles, which had playoff implications for both sides. The Rams were already in the playoffs but could clinch the NFC West title with a win, while the 49ers needed a win to make it into the playoffs. The Rams held a 17–0 lead late in the second quarter, but the 49ers came back to win 27–24 in overtime, clinching a playoff spot. Ultimately, the Rams won the NFC West anyway as the Arizona Cardinals lost their final game.
On January 30, 2022, the 49ers and Rams met in Los Angeles and competed against each other in the NFC Championship Game for the right to represent the NFC in Super Bowl LVI. Despite losing six consecutive regular-season matchups against the 49ers and facing a 10-point deficit heading into the fourth quarter, McVay's Rams came back to defeat San Francisco.[8] After finally defeating their rival, the Rams ultimately went on to win Super Bowl LVI.
In 2019, 49ers' wide receiver Deebo Samuel developed a controversial notoriety for his public feud with the Rams, most notably Los Angeles' former star-defensive tackle Aaron Donald. Following a 2019 home loss against the 49ers in Week 6, Donald was asked about his opinion of Samuel; responding "I don't know who that is". Samuel took to multiple media outlets to attack Donald in the games that followed, claiming: "I don't see how he wouldn't know who I am 'cause he should by now". Samuel would continue to insult the Rams over Twitter during the 49ers' then-ongoing 6-game win streak over Los Angeles. The two teams later met in the 2021-22 NFC Championship Game, culminating in a heated battle between the two. Rams' safety Nick Scott sought retribution for Samuel's previous comments, culminating in Scott violently charging at Samuel with a fierce blindside hit, knocking Samuel to the ground.[21] Samuel was briefly taken out of play by medical staff, however; Scott was not penalized for the hit. Following the Rams' victory in the NFC Championship, Samuel was later seen crying on the sideline, though Rams' receiver Odell Beckham Jr. walked over to comfort him before Samuel covered his face with a towel and walked into the locker room sobbing.[22] Following the victory, Aaron Donald was again asked about his feud with Samuel, responding humorously "who is that again?".[23] Following a Rams loss to the 49ers in Santa Clara on Monday Night Football during the 2022 season, Samuel uploaded a video to Twitter taunting cornerback Jalen Ramsey for failing to cover him during a play. Ramsey and numerous players later mocked Samuel's gesture, explaining that he was assigned to cover Brandon Aiyuk instead.[24] Samuel's comments against the Rams persisted during their season opener on September 17, 2023 against the 49ers. Prior to halftime, Samuel instigated an on-field altercation with Rams' cornerback Derion Kendrick, but was bizarrely interrupted when a 49ers fan jumped onto the field into the melee and began attacking Kendrick until the fan was removed by stadium security. Samuel later jokingly praised the fan's misconduct during his postgame interview to further taunt Kendrick.[25] [26] While in attendance at the 2024 Pro Bowl Games, a 49ers fan in attendance later demanded an autograph from Rams' rookie receiver Puka Nacua. Nacua had taken notice of the fan passing him a Deebo Samuel jersey and jokingly pretended to sign the fan's jersey before tossing it back into the stands as a subtle insult at Samuel for his previous comments.[27] [28]
Due to the intensity brought on by the rivalry following the Rams’ return to Los Angeles, multiple incidents have occurred between rival fans. Similarly to the Dodgers–Giants rivalry of the MLB, the two cities have harbored much animosity towards each other due to the cultural and economic differences across the state. Rams fans often refer to the 49ers as the “Whiners” due to the perception of their fans and players complaining about the referees and blaming external factors for their losses in both the regular season and playoffs. 49ers fans in turn often refer to the Rams as the “Lambs” due to the team's perceived weakness and lack of championship titles through the 1980s and mid-2000s. Both fans also heavily engage in Schadenfreude, especially during the Super Bowl when either team is playing.
As a result of the Rams' absence for 20 seasons and the success of the 49ers during the 1980s and early 1990s, many 49ers fans often attempt to overtake Rams home games against San Francisco. The Rams have seen a recent resurgence in fan support following recent playoff success in the late 2010s. Despite the regrowth of the Rams’ fanbase, the 49ers fanbase often attempt to undermine that of the Rams, given their history within the state; however they regularly devolve into unruly, obnoxious, or violent behavior on numerous occasions.[29] [30] The 2021-22 NFC Championship would see former-Los Angeles Mayor Eric Garcetti and California Governor (former San Francisco Mayor) Gavin Newsom in attendance at SoFi Stadium.[31]
On January 30, 2022, following the Rams’ victory in the NFC Championship game; Daniel Luna, a 40-year-old 49ers fan and chef from Oakland, California; instigated a physical altercation with several Rams fans in the SoFi Stadium parking lot. Witnesses later reported that Luna was possibly intoxicated and was punched multiple times by a suspect; later identified as 33-year-old Rams fan Bryan Alexis Cifuentes of Los Angeles. Footage showed Luna and multiple 49ers fans surrounding Cifuentes and shoving him whilst he was walking to his car, prompting Cifuentes to throw several punches at Luna.[43] After receiving several blows to the chest and head, Luna fell to the ground; hitting his head on the pavement and knocking him unconscious. Cifuentes later fled the scene, returning to his family. Luna was rushed to UCLA Medical Center in Westwood with non-life-threatening injuries. Although he was hospitalized as a result of his concussion, Luna eventually emerged from his coma on March 9, and filed a lawsuit against the Rams and the city of Inglewood on September 9, 2022, for the incident, citing inadequate security; however, the lawsuit was later dropped per video evidence of Luna's conduct during the incident.[44] [45] Representatives of the 49ers management released a statement expressing their disapproval of both Luna and Cifuentes’ actions in the incident.[46] During the trial, Cifuentes would plead not guilty to the assault and claimed the attack was in self-defense after Luna had allegedly shoved him in the back and punched him in the jaw.[47] [48] The court later dropped the Rams and the city of Inglewood as defendants from the case on August 26, 2023.[49] On December 7th, prosecutors examined surveillance footage; showing that Luna was visibly intoxicated at the time and was turned away from the stadium gates due to not having a ticket. On January 15, 2024, jurors concluded that Luna was intoxicated beyond any reasonable judgement during the incident.[50] The case is currently awaiting a final judgement.[51]
|-| | style="| | style="| Rams
35–14| style="| Rams
28–21| Rams
2–0| 49ers move from the All-America Football Conference and are placed in the NFL Western Conference along with the Rams. |-| | Tie 1–1| style="| 49ers
44–17| style="| Rams
23–16| Rams
3–1| Rams win 1951 NFL Championship.|-| | style="| | style="| Rams
34–21| style="| Rams
35–9| Rams
5–1| |-| | style="| | style="| 49ers
31–30| style="| 49ers
31–27| Rams
5–3| |-| | style="| | style="| Rams
42–34| Tie
24–24| Rams
6–3–1| |-| | style="| | style="| Rams
23–14| style="| Rams
27–14| Rams
8–3–1| Rams lose 1955 NFL Championship.|-| | Tie 1–1| style="| 49ers
33–30| style="| Rams
30–6| Rams
9–4–1| |-| | Tie 1–1| style="| 49ers
23–20| style="| Rams
37–24| Rams
10–5–1| The Rams' home game was played in front of 102,368 fans, an NFL attendance record that stood until 2009.|-| | style="| | style="| Rams
33–3| style="| Rams
56–7| Rams
12–5–1| The Rams' 56–7 win is the biggest blowout in the history of the rivalry.|-| | style="| | style="| 49ers
34–0| style="| 49ers
24–16| Rams
12–7–1| |-|-| | style="| | style="| 49ers
23–7| style="| 49ers
13–9| Rams
12–9–1| |-| | Tie 1–1| style="| 49ers
35–0| style="| Rams
17–7| Rams
13–10–1| |-| | Tie 1–1| style="| Rams
28–14| style="| 49ers
24–17| Rams
14–11–1| |-| | style="| | style="| Rams
21–17| style="| Rams
28–21| Rams
16–11–1| |-| | Tie 1–1| style="| 49ers
28–7| style="| Rams
42–14| Rams
17–12–1| |-| | style="| | style="| 49ers
45–21| style="| 49ers
30–27| Rams
17–14–1| |-| | Tie 1–1| style="| 49ers
21–13| style="| Rams
34–3| Rams
18–15–1| |-| | Tie 1–1| style="| Rams
17–7| style="| 49ers
27–24| Rams
19–16–1| |-| | style="| | Tie
20–20| style="| Rams
24–10| Rams
20–16–2||-| | style="| | style="| Rams
27–21| style="| Rams
41–30| Rams
22–16–2| |-|-| | Tie 1–1| style="| Rams
30–13| style="| 49ers
20–6| Rams
23–17–2| Both teams placed in the NFC West after AFL-NFL merger.|-| | style="| | style="| Rams
20–13| style="| Rams
17–6| Rams
25–17–2| 49ers open Candlestick Park.|-| | style="| | style="| Rams
26–16| style="| Rams
31–7| Rams
27–17–2| |-| | style="| | style="| Rams
37–14| style="| Rams
31–13| Rams
29–17–2| |-| | style="| | style="| Rams
15–13| style="| Rams
37–14| Rams
31–17–2||-| | Tie 1–1| style="| Rams
23–14| style="| 49ers
24–23| Rams
32–18–2| The Rams win 10 straight meetings (1970–75).|-| | Tie 1–1| style="| Rams
23–3| style="| 49ers
16–0| Rams
33–19–2||-| | style="| | style="| Rams
23–10| style="| Rams
34–14| Rams
35–19–2| |-| | style="| | style="| Rams
31–28| style="| Rams
27–10| Rams
37–19–2| |-| | style="| | style="| Rams
26–20| style="| Rams
27–24| Rams
39–19–2| Rams lose Super Bowl XIV.|-|-| | style="| | style="| Rams
31–17| style="| Rams
48–26| Rams
41–19–2 | The Rams win 12 straight games in San Francisco (1969–80). Rams move to Anaheim Stadium.|-| | style="| | style="| 49ers
20–17| style="| 49ers
33–31| Rams
41–21–2| 49ers sweep season series for the first time since 1965. 49ers win Super Bowl XVI.|-| | Tie 1–1| style="| Rams
21–20| style="| 49ers
30–24| Rams
42–22–2| Both games played despite players strike reducing the season to 9 games. Rams block a potential 49ers' game-winning field goal in the final seconds of the game in San Francisco.|-| | Tie 1–1| style="| Rams
10−7| style="| 49ers
45−35| Rams
43–23–2 | |-| | style="| | style="| 49ers
19–16| style="| 49ers
33–0| Rams
43–25–2| 49ers win Super Bowl XIX.|-| | Tie 1–1| style="| Rams
27–20| style="| 49ers
28–14| Rams
44–26–2 | |-| | Tie 1–1| style="| 49ers
24–14| style="| Rams
16–13| Rams
45–27–2 | |-| | style="| | style="| 49ers
48–0| style="| 49ers
31–10| Rams
45–29–2||-| | Tie 1–1| style="| Rams
38–16| style="| 49ers
24–21| Rams
46–30–2 | 49ers win Super Bowl XXIII.|-| | Tie 1–1| style="| Rams
13–12| style="| 49ers
30–27| Rams
47–31–2 | 49ers win Super Bowl XXIV. The game at Anaheim saw John Taylor become the first receiver in NFL history to score 2 touchdowns of 90 yards or longer in the same game.|- style="font-weight:bold;background:#f2f2f2;"| 1989 Playoffs| style="| | style="| 49ers
30–3| | Rams
47–32–2| NFC Championship Game. First playoff meeting between the two teams.|-|-| | Tie 1–1| style="| Rams
28–17| style="| 49ers
26–10| Rams
48–33–2 | The game at San Francisco marked the 49ers' first loss of the 1990 season, as well as being the Rams' last win over the 49ers until 1999.|-| | style="| | style="| 49ers
27–10| style="| 49ers
33–10| Rams
48–35–2| |-| | style="| | style="| 49ers
27–24| style="| 49ers
27–10| Rams
48–37–2| |-| | style="| | style="| 49ers
40–17| style="| 49ers
35–10| Rams
48–39–2| |-| | style="| | style="| 49ers
31–27| style="| 49ers
34–19| Rams
48–41–2| 49ers win Super Bowl XXIX.|-| | style="| | style="| 49ers
41–13| style="| 49ers
44–10| Rams
48–43–2| Rams re-locate to St. Louis, play at Busch Memorial Stadium for the first half of the 1995 season, with the meeting in St. Louis being the last home game before Trans World Dome was completed.|-| | style="| | style="| 49ers
34–0| style="| 49ers
28–11| Rams
48–45–2| |-| | style="| | style="| 49ers
30–10| style="| 49ers
15–12| Rams
48–47–2| |-| | style="| | style="| 49ers
38–19| style="| 49ers
28–10| 49ers
49–48–2| The 49ers win 17 straight meetings (1990–98) and 12 straight meetings in LA/St. Louis (1987–98). The 49ers take the lead in the series for the first time.|-| | style="| | style="| Rams
23–7| style="| Rams
42–20| Rams
50–49–2 | Rams' first season sweep since 1980. Rams win Super Bowl XXXIV.|-|-| | style="| | style="| Rams
34–24| style="| Rams
41–24| Rams
52–49–2 | |-| | style="| | style="| Rams
30–26| style="| Rams
27–14| Rams
54–49–2 | Rams lose Super Bowl XXXVI.|-| | Tie 1–1| style="| 49ers
37–13| style="| Rams
31–20| Rams
55–50–2 | |-| | Tie 1–1| style="| 49ers
30–10| style="| Rams
27–24(OT)| Rams
56–51–2 | |-| | style="| | style="| Rams
24–14| style="| Rams
16–6| Rams
58–51–2 | |-| | style="| | style="| 49ers
28–25| style="| 49ers
24–20| Rams
58–53–2| |-| | Tie 1–1| style="| 49ers
20–13| style="| Rams
20–17| Rams
59–54–2 | |-| | Tie 1–1| style="| Rams
13–9| style="| 49ers
17–16| Rams
60–55–2 | |-| | style="| | style="| 49ers
35–16| style="| 49ers
17–16| Rams
60–57–2| |-| | style="| | style="| 49ers
35–0| style="| 49ers
28–6| Rams
60–59–2| |-|-| | Tie 1–1| style="| 49ers
23–20(OT)| style="| Rams
25–17| Rams
61–60–2| |-| | style="| | style="| 49ers
26–0| style="| 49ers
34–27| 49ers
62–61–2| |-| | style="| | Tie
| style="| Rams
| Tie
62–62–3| Only tie the game in the series since the 1974 introduction of overtime in regular season games. The Rams had what would have been a game-winning field goal taken away because of a penalty. The Rams kicked a field goal as time expired in OT of the second game, narrowly averting a second straight tie. 49ers lose Super Bowl XLVII.|-| | style="| | style="| 49ers
23–13| style="| 49ers
35–11| 49ers
64–62–3| |-| | Tie 1–1| style="| Rams
13–10| style="| 49ers
31–17| 49ers
65–63–3| 49ers open Levi's Stadium in Santa Clara.|-| | Tie 1–1| style="| 49ers
19–16(OT)| style="| Rams
27–6| 49ers
66–64–3| The game in Santa Clara is the Rams’ last game as a St. Louis-based franchise.|-| | style="| | style="| 49ers
28–0| style="| 49ers
22–21| 49ers
68–64–3| Rams return to the Los Angeles Memorial Coliseum in LA. The 49ers' wins over the Rams are their only wins in a 2–14 season. 49ers' 9th shutout win in team history vs. Rams. Rams draft Jared Goff.|-| | Tie 1–1| style="| Rams
41–39| style="| 49ers
34–13| 49ers
69–65–3| First matchup between Sean McVay as coach of the Rams, and Kyle Shanahan as coach of the 49ers.|-| | style="| | style="| Rams
39–10| style="| Rams
48–32| 49ers
69–67–3| Rams sweep season series for the first time since 2004 and clinch a first-round bye in their home win in week 17. Rams lose Super Bowl LIII.|-| | style="| | style="| 49ers
34–31| style="| 49ers
20–7| 49ers
71–67–3| 49ers eliminate the Rams from playoff contention with a win in Santa Clara. 49ers lose Super Bowl LIV.|-|-| | style="| | style="| 49ers
24–16| style="| 49ers
23–20| 49ers
73–67–3| No fans in attendance for either game due to COVID-19 pandemic. Rams open SoFi Stadium in Inglewood.|-| | style="| | style="| 49ers
31–10| style="| 49ers
| 49ers
75–67–3| Rams trade Jared Goff for Matthew Stafford. 49ers overcome 17–0 deficit, clinch a playoff berth in the game in Los Angeles. |-|- style="font-weight:bold;background:#f2f2f2;"| 2021 Playoffs| style="|
| | style="| Rams
20–17 | 49ers
75–68–3| NFC Championship Game. Rams come back from 17–7 deficit in fourth quarter. Rams go on to win Super Bowl LVI|-| | style="| | style="| 49ers
24–9| style="| 49ers
31–14| 49ers
77–68–3| The Rams finish the season with a 5–12 record, becoming the worst defending champion in the Super Bowl era. 49ers lose NFC Championship game to Philadelphia Eagles.|- | | Tie 1–1| style="| Rams
21–20| style="| 49ers
30–23| 49ers
78–69–3| 49ers win 9 straight regular-season meetings (2019–2023). 49ers lose Super Bowl LVIII.|-|-| Regular season| style="|| 49ers 37–35–2| 49ers 40–33–1| 49ers lead the series in Los Angeles 29–23–1 and won the series in St. Louis 11–10|-| Postseason| Tie 1–1| 49ers 1–0| Rams 1–0| NFC Championship Game: 1989, 2021|-| Regular and postseason | style="|| 49ers 38–35–2| 49ers 40–34–1| |-