4-trimethylammoniobutyraldehyde dehydrogenase explained

4-trimethylammoniobutyraldehyde dehydrogenase
Ec Number:1.2.1.47
Cas Number:73361-01-0
Go Code:0047105

In enzymology, a 4-trimethylammoniobutyraldehyde dehydrogenase is an enzyme that catalyzes the chemical reaction

4-trimethylammoniobutanal + NAD+ + H2O

\rightleftharpoons

4-trimethylammoniobutanoate + NADH + 2 H+

The 3 substrates of this enzyme are 4-trimethylammoniobutanal, NAD+, and H2O, whereas its 3 products are 4-trimethylammoniobutanoate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-trimethylammoniobutanal:NAD+ 1-oxidoreductase. Other names in common use include 4-trimethylaminobutyraldehyde dehydrogenase, and 4-N-trimethylaminobutyraldehyde dehydrogenase. This enzyme participates in lysine degradation and carnitine biosynthesis.

See also

References