4-Hydroxytestosterone Explained

4-Hydroxytestosterone (4-OHT), also known as 4,17β-dihydroxyandrost-4-en-3-one, is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone that was never marketed. It was first patented by G.D. Searle & Company in 1955^[1] and is testosterone with a hydroxy group at the four position. 4-OHT has moderate anabolic, mild androgenic, and anti-aromatase properties and is similar to the steroid clostebol (4-chlorotestosterone).^[2]

See also

• 4-Androstene-3,6,17-trione
• Androstenedione
• Enestebol
• Formestane
• 11β-Hydroxytestosterone

Notes and References

1. US . 2762818 . Levy H, Mednick ML . GD Searle . 4-Hydroxytestosterone and esters . . . 26 May 1955 . 11 September 1956 .
2. Kohler M, Parr MK, Opfermann G, Thevis M, Schlörer N, Marner FJ, Schänzer W . Metabolism of 4-hydroxyandrostenedione and 4-hydroxytestosterone: Mass spectrometric identification of urinary metabolites . Steroids . 72 . 3 . 278–86 . March 2007 . 17207827 . 10.1016/j.steroids.2006.11.018 . 34982808 .