P-Hydroxynorephedrine Explained

p-Hydroxynorephedrine (PHN), or 4-hydroxynorephedrine, is the para-hydroxy analog of norephedrine and an active sympathomimetic metabolite of amphetamine in humans.[1] [2] When it occurs as a metabolite of amphetamine, it is produced from both p-hydroxyamphetamine and norephedrine.[3] [4]

Amphetamine metabolism

See also

Notes and References

  1. Web site: p-Hydroxynorephedrine. NCBI. PubChem Compound. 25 October 2013.
  2. Web site: Adderall XR Prescribing Information . Medication Guide . United States Food and Drug Administration . 7 October 2013.
  3. Web site: Amphetamine: Biomedical Effects and Toxicity. NCBI. Pubchem Compound. 12 October 2013.
  4. Santagati NA, Ferrara G, Marrazzo A, Ronsisvalle G . Simultaneous determination of amphetamine and one of its metabolites by HPLC with electrochemical detection . J. Pharm. Biomed. Anal. . 30 . 2 . 247–55 . September 2002 . 12191709 . 10.1016/S0731-7085(02)00330-8 .

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