4-hydroxybenzoyl-CoA thioesterase explained
| 4-hydroxybenzoyl-CoA thioesterase |
| Ec Number: | 3.1.2.23 |
| Cas Number: | 141583-19-9 |
| Go Code: | 0018739 |
The enzyme 4-hydroxybenzoyl-CoA thioesterase (EC 3.1.2.23) catalyzes the reaction
4-hydroxybenzoyl-CoA + H2O
4-hydroxybenzoate + CoA
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is 4-hydroxybenzoyl-CoA hydrolase. This enzyme participates in 2,4-dichlorobenzoate degradation.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes,,,,,, and .
References
- Chang KH, Liang PH, Beck W, Scholten JD, Dunaway-Mariano D . 1992 . Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3 . Biochemistry . 31 . 5605–10 . 1610806 . 10.1021/bi00139a025 . 24 .
- Dunaway-Mariano D, Babbitt PC . 1994 . On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway . Biodegradation . 5 . 259–76 . 7765837 . 10.1007/BF00696464 . 3–4 . 13250105 .
